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Broccoli Extract Inhibits Growth of Breast Cancer Cells

by Keith D. Bishop, Clinical Nutritionist, B.Sc. Pharmacy - September 10, 2009

  • Sulforaphane, a broccoli extract, inhibited the growth of breast cancer cells in rats and human cell lines. 

Broccoli extract sulforaphane may decrease the risk of breast cancer.Sulforaphane, an isothiocyanate found in cruciferous vegetables has been shown to inhibit the growth of chemically induced breast cancer tumors in rats. Sulforaphane induces phase 2 liver detoxification enzymes and inhibits the growth of chemically induced mammary tumors n rats. Phase 2 liver detoxification helps the liver remove toxic chemicals from the body.

In this study researchers found that Sulforaphane inhibits breast cancer cell growth, activates apoptosis, inhibits histone deacetylase (HDAC), and decreases the expression of key proteins involved in breast cancer proliferation in human breast cancer cells.

Researchers state “These results support testing Sulforaphane in vivo (in the body) and warrant future studies examining the clinical potential of Sulforaphane in human breast cancer.”

Reference Source: Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines. Pledgie-Tracy A, Sobolewski MD, Davidson NE., Mol Cancer Ther. 2007 Mar;6(3):1013-21.

Natural Cancer Reports Pearl:
Sulforaphane helps the liver remove toxic chemicals and heterocyclic amnes from the body. Sulforaphane improves the removal of heterocyclic amines that come from browning, grilling or burning meats and other foods.

Hamburgers have a very high quantity of heterocyclic amines. A hamburger patty is typically cooked at a very high temperature. The browning,  charring or blackening meat, vegetables and even the smoke contain the toxic heterocyclic amines.

If you have a personal history of breast, prostate or colon cancer you can take a Sulforaphane capsule with your meals that contain grilled, broiled, baked or fried foods. You should cook meats at low temperature. Don’t cook your meat well done or blackened. Use olive oil based marinade on vegetables and meat prior to cooking to decrease browning.

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About the Author:

Keith D. Bishop, Clinical Nutritionist, B.Sc. Pharmacy helps his clients improve their health by using natural products, tests and self care. He writes special reports on natural product, diet and lifestyle effects on cancer. You may schedule an appointment for customized natural cancer recommendations by calling 405.919.1982.

Click here to learn more about Alternative Cancer Treatment Appointments.


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