Keith D. Bishop, Clinial Nutritionist, B.Sc. Pharmcy - September 9, 2011
Colorectal Cancer Prevention - Take This Supplement to Increase Cancer Risks and Speed Aging
A high dose of folic acid increases the risk of colorectal cancer and accelerated aging.
A study of 781 patients compared folate and aspirin in the
prevention of pre-cancerous colorectal polyps. After 3 years researchers found high folate levels decreased the
activity of tumor-suppressing genes and added 10 years of extra aging to cells in the
Researchers state: “These findings suggest that people supplementing with extra folate may be increasing their risk
of developing certain cancers and age-related diseases."
Reference Source: Wallace K, Grau MV, Levine AJ, et al. Association between folate levels and CpG Island
hypermethylation in normal colorectal mucosa. Cancer Prev Res. Dec 2010;3(12):1552-64.
Colorectal Cancer Prevention Pearl
Folic Acid taken before and during pregnancy does decrease the risk of birth defects. But, Folic Acid in
vitamins may be too strong for some people after child bearing years. Due to genetic issues up to 60% of the
population cannot convert Folic Acid found in vitamins and food into the active form 5 methyl-tetrahydrofolate.
Colorectal Cancer Prevention Tip: How do you know if you may have a problem
converting Folic Acid into the active 5 methyl-tetrahydrofolate?
- Bet a blood test for the MTHFR SNP. If you have the MTHFR SNP you should avoid folic acid supplements and
select products with 5 methyl-tetrahydrofolate. This is expensive and hard to find.
- Stop taking your B vitamin supplement for 2 months. Get a blood test for Homocysteine. If your Homocysteine
level is higher than 7 you may have a genetic problem converting Folic Acid in the safer 5
methyl-tetrahydrofolate. If your homocysteine is above 7 and you have a family or personal history of cancer
you should avoid Folic Acid in your supplements and select products with 5 methyl-tetrahydrofolate.
It’s unknown at this time if calcium folinate or folinic acid are safer than Folic Acid.
Return form Colorectal Cancer Prevention Natural Cancer News to 2011
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