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EGCG & Curcumin Inhibit Prostate Cancer Cell Growth

Keith D. Bishop, Clinical Nutritionist, B.Sc. Pharmacy - 01/07/2015

  • EGCG combined with curcumin inhibits prostate cancer cell growth in a laboratory study.  

 
EGCG (Epigallocatechin gallate) and curcumin are well known natural anticancer agents. In laboratory studies researchers evaluated the combined effect of curcumin and EGCG on PC3 prostate cancer cells, which are resistant to chemotherapy.

EGCG and Curcumin Inhibit prostate cancer cell growthEGCG showed weak growth inhibition effect on the PC3 prostate cancer cells and stronger growth inhibition effect on LNCaP and DU145 prostate cancer cell lines.

Co-treatment of curcumin improved the growth inhibition effect on EGCG on PCE prostate cancer cells. The co-treatment of curcumin and EGCG arrested both S and G2/M phases of cell division and growth of the PC3 cells.

Curcumin is not well absorbed. I recommend taking curcumin with BioPerine (black pepper extract) to increases the absorption and blood levels of curcumin. Diindolylmethane also has research supporting its use against prostate cancer. 
Click here to learn about DIMension 3 (curcumin, diindolylmethane, and BioPerine) by Xymogen.

I use Xymogen Green Tea 600 for therapeutic source of EGCG. Click here to learn about Green Tea 600.

There are different types of prostate cancer cell lines with different types of aggressiveness and sensitivity to chemotherapy, radiation and alternative treatments. This article mentioned 3 cells lines. There are others. At the time I wrote this article doctors are NOT testing prostate cells obtained from biopsies or prostate removal for cell lines. Please ask your doctor what your prostate cancer cell line is. They will probably not have that information, but it will serve to enlighten them about prostate cancer cell lines. Perhaps in the future men with prostate cancer will be able to customize their traditional and natural treatment to improve their outcomes.

About the Author:

Keith D. Bishop, Clinical Nutritionist, B.Sc. Pharmacy (retired pharmacist), helps his clients improve their health by using natural products, functional tests, diet, lifestyle and self care. He writes special reports, consults and gives seminars on natural product, diet and lifestyle effects on cancer. You may schedule an appointment for customized natural cancer or alternative cancer recommendations by calling 405.919.1982.

Click here to learn more about Alternative Cancer Treatment Appointments.


BMB Reports. 2014 Dec 2. Synergistic effect of curcumin on epigallocatechin gallate-induced anticancer action in PC3 prostate cancer cells. Eom DW, Lee JH, et al.

Source: http://submit.bmbreports.org/Search/View.html?tr_num=2990&start=0&keyword=

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