Successfully Integrating Alternative Cancer Treatment and Natural Cancer Treatment Strategies

Ewing's Sarcoma Alternative Treatment

Ewing's Sarcoma Alternative TreatmentEwing's Sarcoma Alternative Treatment Strategies Based on Medical Research

Curcumin and Ewing's Sarcoma

Curcumin enhances the effectiveness of radiation therapy on Ewing’s Sarcoma cells. [i] In laboratory studies curcumin stopped Ewing’s Sarcoma cells from growing and caused cancer cell death. [ii] At the time of publication there are no animal or human studies of curcumin and Ewing’s Sarcoma. 

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EGCG (epigallocatechin gallate) and Ewing's Sarcoma

In a laboratory study researchers found EGCG, from green tea, can inhibit cell growth and survival of Ewing tumors. The higher the dose and longer the exposure the better the anticancer effects. [iii] At the time of publication there are no animal or human studies of EGCG and Ewing’s Sarcoma. 

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Vitamin A and Ewing's Sarcoma 

Vitamin A added to Ewing’s sarcoma cells stopped cancer cell growth and encouraged normal cancer cell death. [iv] At the time of publication there are no animal or human studies of Vitamin A and Ewing’s Sarcoma. 

Melatonin and Ewing's Sarcoma

Melatonin increases oxidative damage and death of Ewing’s sarcoma cancer cells. At the time of publication there are no animal or human studies of melatonin and Ewing’s Sarcoma.  [v]  [vi] 

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Ewing's Sarcoma Alternative Treatment Research References

[i] Anticancer Research. 2010 Oct;30(10):4007-15. Curcumin-altered p53-response genes regulate radiosensitivity in p53-mutant Ewing's sarcoma cells. Veeraraghavan J1, Natarajan M, et al. Department of Radiation Oncology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.  

[ii] Medical Oncology. 2010 Dec;27(4):1096-101. Cell cycle inhibition and apoptosis induced by curcumin in Ewing sarcoma cell line SK-NEP-1. Singh M1, Pandey A, et al. All India Institute of Medical Sciences, New Delhi, India.    

[iii] Molecular Cancer Therapeutics. 2010 May;9(5):1396-407. doi: 10.1158/1535-7163.MCT-09-0604. Epub 2010 Apr 27. Inhibition of the insulin-like growth factor I receptor by epigallocatechin gallate blocks proliferation and induces the death of Ewing tumor cells. Kang HG1, Jenabi JM, et al. Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.  

[iv] Clinical Cancer Research. 1998 Mar;4(3):755-61. Synergistic effects of 8-chlorocyclic-AMP and retinoic acid on induction of apoptosis in Ewing's sarcoma CHP-100 cells. Srivastava RK1, Srivastava AR, et al. Cellular Biochemistry Section, Laboratory of Tumor Immunology and Biology, National Cancer Institute, Bethesda, Maryland 20892, USA.  

[v] British Journal of Cancer. 2012 Mar 27;106(7):1288-96. Fas/Fas ligand regulation mediates cell death in human Ewing's sarcoma cells treated with melatonin. García-Santos G1, Martin V, et al. Departamento de Morfología y Biología Celular, Facultad de Medicina, Universidad de Oviedo, C/ Julian Claveria 6, 33006 Oviedo, Spain.    

[vi] Journal of Pineal Research. 2010 Jan;48(1):72-80. Synergistic antitumor effect of melatonin with several chemotherapeutic drugs on human Ewing sarcoma cancer cells: potentiation of the extrinsic apoptotic pathway. Casado-Zapico S1, Rodriguez-Blanco J, et al. Instituto Universitario de Oncología del Principado de Asturias (IUOPA), c/Julian Claveria, Oviedo, Spain.;jsessionid=D92ABFA012D04B014C0837BE9B26CE19.f01t04