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Green Tea and Oral Cancer

Green Tea and Oral Cancer - EGCG in green tea kills oral cancer cells in laboratory studies.

Green Tea and Oral Cancer EGCGEpigallocatechin-3-gallate (EGCG) is the major bioactive component of green tea. EGCG has been shown to inhibit the proliferation of many cancers. Studies have also shown drinking green tea can reduce the incidence of Nasopharyngeal Carcinoma (NCP).

Oral squamous cell carcinoma (OSCC) accounts form most oral cancers.

In a laboratory cancer cell study researchers treated SSC-4 human oral squamous cell carcinoma (OSCC) cells with EGCG extract. EGCG caused the OSCC cells to die in a dose and time dependent manner. In other words the higher the dose and the longer exposure to EGCG the better the results.

The researchers stated "EGCG has an excellent potential to become a therapeutic coumpound for patients with OSCC, by inducing tumor cell death via apoptosis and autophagy." 

Another group of researchers planted OSCC cells into animals. EGCG supplements decreased the oral cancer tumor cell growth.

Yet another group of researchers found treatment with EGCG from green tea inhibited the growth of NCP cells by did not affect the growth of non-magnlignant cells. EGCG also reduced the migration and invasion of the cancer cells.

The researchers stated "EGCG can inhibit the proliferation and invasiveness, and induce apoptosis, of NPC cells, making it a promising agent for chemoprevention or adjuvant therapy of NPC."

These research studies used concentrated EGCG powder. You can not get eough EGCG from drinking green tea. EGCG extract capsules are available.

Click or tap here to learn about Green Tea 600 by Xymogen. 

Click or tap here to read more Natural Oral Cancer Treatment Stratgies.

Reference Sources
Onco Targets and Therapy. 2015 Feb 20;8:461-70. Epigallocatechin-3-gallate suppresses cell proliferation and promotes apoptosis and autophagy in oral cancer SSC-4 cells.

2015 Feb 23. Upregulation of B-cell translocation gene 2 by epigallocatechin-3-gallate via p38 and ERK signaling blocks cell proliferation in human oral squamous cell carcinoma cells. Lee JC, Chung LC, et al.

2015 Jan 23;16(2):2530-58. EGCG Inhibits Proliferation, Invasiveness and Tumor Growth by Up-Regulation of Adhesion Molecules, Suppression of Gelatinases Activity, and Induction of Apoptosis in Nasopharyngeal Carcinoma Cells. Fang CY, Wu CC, et al.

Return from Green Tea and Oral Cancer to 2015 Natural Cancer News.