Sprout Extract Inhibits Growth of Breast Cancer Cells
Written by Keith D. Bishop, Clinical Nutritionist, B.Sc. Pharmacy, Health Coach - January 19,
Breast Cancer Broccoli: Sulforaphane, a broccoli sprout extract, inhibited the growth of breast cancer
Sulforaphane, an isothiocyanate found in broccoli and other cruciferous vegetables has been
shown to inhibit the growth of chemically induced breast cancer tumors in rats. Sulforaphane induces phase 2
liver detoxification enzymes and inhibits the growth of chemically induced mammary tumors n rats. Phase 2
liver detoxification helps the liver remove toxic chemicals from the body.
In this study researchers found that sulforaphane inhibits breast cancer cell growth,
activates apoptosis, inhibits histone deacetylase (HDAC), and decreases the expression of key proteins involved in
breast cancer proliferation in human breast cancer cells.
Researchers state “These results support testing sulforaphane in vivo and warrant future studies examining the
clinical potential of sulforaphane in human breast cancer.”
Reference Source: Sulforaphane induces cell
type-specific apoptosis in human breast cancer cell lines. Pledgie-Tracy A, Sobolewski MD, Davidson NE., Mol
Cancer Ther. 2007 Mar;6(3):1013-21.
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Sulforaphane helps the liver remove toxic chemicals from the body. Sulforaphane
improves the removal of heterocyclic amines that come from browning, grilling or burning meats and other
Hamburgers have one of the highest quantities of heterocyclic amines. A hamburger
patty is typically cooked at a very high temperature. The charred or blackened meat, vegetables and smoke contain
the toxic heterocyclic amines. Heterocyclic amines are a risk factor for breast cancer, prostate cancer and several
If you have a personal history of breast, prostate or colon cancer take a
Sulforaphane capsule with your meals that contain grilled, broiled, baked or fried foods. Cook meats at low
temperature. Don’t cook your well done or blackened. Use olive oil based marinade on vegetables and meat prior to
cooking to decrease browning or burning.
OncoPLEX provides Sulforaphane Nutritional Support for Cancer Risk, Gastritis, H.
pylori, Age-related Macular Degeneration, Hypertension, Cardiovascular Inflammation and Arthritis.
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