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Broccoli Sprout Extract Inhibits Growth of Breast Cancer Cells

Written by Keith D. Bishop, Clinical Nutritionist, B.Sc. Pharmacy, Health Coach - January 19, 2010

  • Breast Cancer Broccoli: Sulforaphane, a broccoli sprout extract, inhibited the growth of breast cancer cells. 

Breast Cancer Broccoli Sprouts Inhibits Growth of Breast Cancer CellsSulforaphane, an isothiocyanate found in broccoli and other cruciferous vegetables has been shown to inhibit the growth of chemically induced breast cancer tumors in rats. Sulforaphane induces phase 2 liver detoxification enzymes and inhibits the growth of chemically induced mammary tumors n rats. Phase 2 liver detoxification helps the liver remove toxic chemicals from the body.

In this study researchers found that sulforaphane inhibits breast cancer cell growth, activates apoptosis, inhibits histone deacetylase (HDAC), and decreases the expression of key proteins involved in breast cancer proliferation in human breast cancer cells.

Researchers state “These results support testing sulforaphane in vivo and warrant future studies examining the clinical potential of sulforaphane in human breast cancer.”

Reference Source: Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines. Pledgie-Tracy A, Sobolewski MD, Davidson NE., Mol Cancer Ther. 2007 Mar;6(3):1013-21.

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Sulforaphane helps the liver remove toxic chemicals from the body. Sulforaphane improves the removal of heterocyclic amines that come from browning, grilling or burning meats and other foods.

Hamburgers have one of the highest quantities of heterocyclic amines. A hamburger patty is typically cooked at a very high temperature. The charred or blackened meat, vegetables and smoke contain the toxic heterocyclic amines. Heterocyclic amines are a risk factor for breast cancer, prostate cancer and several other cancers.

If you have a personal history of breast, prostate or colon cancer take a Sulforaphane capsule with your meals that contain grilled, broiled, baked or fried foods. Cook meats at low temperature. Don’t cook your well done or blackened. Use olive oil based marinade on vegetables and meat prior to cooking to decrease browning or burning.

OncoPLEX provides Sulforaphane Nutritional Support for Cancer Risk, Gastritis, H. pylori, Age-related Macular Degeneration, Hypertension, Cardiovascular Inflammation and Arthritis.

Click here to read more Alternative Breast Cancer Treatment Research articles.

About the Author:

Keith D. Bishop, Clinical Nutritionist, B.Sc. Pharmacy helps his clients improve their health by using natural products, functional tests, diet, lifestyle and self care. He writes special reports on natural product, diet and lifestyle effects on cancer. You may schedule an appointment for customized natural cancer recommendations by calling 405.919.1982. Click here to learn more about Alternative Cancer Treatment Appointments.

Keith D. Bishop, is the owner and publisher of and


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